Microbiology, Metagenomics and Bioinformatics

Johan Bengtsson-Palme, University of Gothenburg

Browsing Posts tagged Workshop

I am part of the organizing committee for the newly invented annual meeting for GOTBIN – the Gothenburg Bioinformatics Network. We will arrange a meeting on December 6 to get the networking activities for 2017 kickstarted, and every bioinformatician in Gothenburg is invited!

GOTBIN was launched to bridge and bring together all researchers in Gothenburg who fully or partially dealt with bioinformatics in their research. Through the network it should be possible to quickly find other local researchers tackling the same research problems as you are; to find appropriate resources to run your analyses; and to discuss research or infrastructure problems as they arise. To keep the network alive and kicking, it is crucial to keep relations active. Furthermore, it is also crucial to interact with key persons in the GOTBIN network to keep the lists of active researchers, resources and discussion forums up to date.

To facilitate future communication, we invite everyone who works with bioinformatics in Gothenburg to participate in a get-together workshop. The purpose of this workshop is to find out who is working with what and where, and to better get to know each other. This is a great opportunity to meet your next collaboration partner, post-doc or supervisor! The event will take place in Birgit Thilander at Medicinareberget (just next to the large lecture hall Arvid Carlsson) on December 6th, from 9.00 to 12.00. Fika will be provided and we will arrange ice-breaker activities suitable for the number of participants, so please register at: https://goo.gl/forms/KYdiiZMBDf0F9hvp2 by the 16th of November.

We hope to find everyone with a research interest in bioinformatics there and that this will be the launch of the next era of GOTBIN in 2017! See you there!

I just want to highlight that the paper on strategies to improve database accuracy and usability we recently published in Proteomics (1) has been included in their most recent issue, which is a special issue focusing on Data Quality Issues in Proteomics. I highly recommend reading our paper (of course) and many of the other in the special issue. Happy reading!

On another note, I will be giving a talk next Wednesday (October 5th) on a seminar day on next generation sequencing in clinical microbiology, titled “Antibiotic resistance in the clinic and the environment – There and back again“. You are very welcome to the lecture hall at floor 3 in our building at Guldhedsgatan 10A here in Gothenburg if you are interested! (Bear in mind though that it all starts at 8.15 in the morning.)

Finally, it seems that I am going to the Next Generation Sequencing Congress in London this year, which will be very fun! Hope to see some of you dealing with sequencing there!

References

  1. Bengtsson-Palme J, Boulund F, Edström R, Feizi A, Johnning A, Jonsson VA, Karlsson FH, Pal C, Pereira MB, Rehammar A, Sánchez J, Sanli K, Thorell K: Strategies to improve usability and preserve accuracy in biological sequence databases. Proteomics, 16, 18, 2454–2460 (2016). doi: 10.1002/pmic.201600034 [Paper link]

MycoKeys today put a paper online which I was involved in. The paper describes the results of a workshop in May, when we added and refined annotations for fungal ITS sequences according to the MIxS-Built Environment annotation standard (1). Fungi have been associated with a range of unwanted effects in the built environment, including asthma, decay of building materials, and food spoilage. However, the state of the metadata annotation of fungal DNA sequences from the built environment is very much incomplete in public databases. The workshop aimed to ease a little part of this problem, by distributing the re-annotation of public fungal ITS sequences across 36 persons. In total, we added or changed of 45,488 data points drawing from published literature, including addition of 8,430 instances of countries of collection, 5,801 instances of building types, and 3,876 instances of surface-air contaminants. The results have been implemented in the UNITE database and shared with other online resources. I believe, that distributed initiatives like this (and the ones I have been involved in in the past (2,3)) serve a very important purpose for establishing better annotation of sequence data, an issue I have brought up also for sequences outside of barcoding genes (4). The full paper can be found here.

References

  1. Abarenkov K, Adams RI, Laszlo I, Agan A, Ambrioso E, Antonelli A, Bahram M, Bengtsson-Palme J, Bok G, Cangren P, Coimbra V, Coleine C, Gustafsson C, He J, Hofmann T, Kristiansson E, Larsson E, Larsson T, Liu Y, Martinsson S, Meyer W, Panova M, Pombubpa N, Ritter C, Ryberg M, Svantesson S, Scharn R, Svensson O, Töpel M, Untersehrer M, Visagie C, Wurzbacher C, Taylor AFS, Kõljalg U, Schriml L, Nilsson RH: Annotating public fungal ITS sequences from the built environment according to the MIxS-Built Environment standard – a report from a May 23-24, 2016 workshop (Gothenburg, Sweden). MycoKeys, 16, 1–15 (2016). doi: 10.3897/mycokeys.16.10000
  2. Kõljalg U, Nilsson RH, Abarenkov K, Tedersoo L, Taylor AFS, Bahram M, Bates ST, Bruns TT, Bengtsson-Palme J, Callaghan TM, Douglas B, Drenkhan T, Eberhardt U, Dueñas M, Grebenc T, Griffith GW, Hartmann M, Kirk PM, Kohout P, Larsson E, Lindahl BD, Lücking R, Martín MP, Matheny PB, Nguyen NH, Niskanen T, Oja J, Peay KG, Peintner U, Peterson M, Põldmaa K, Saag L, Saar I, Schüßler A, Senés C, Smith ME, Suija A, Taylor DE, Telleria MT, Weiß M, Larsson KH: Towards a unified paradigm for sequence-based identification of Fungi. Molecular Ecology, 22, 21, 5271–5277 (2013). doi: 10.1111/mec.12481
  3. Nilsson RH, Hyde KD, Pawlowska J, Ryberg M, Tedersoo L, Aas AB, Alias SA, Alves A, Anderson CL, Antonelli A, Arnold AE, Bahnmann B, Bahram M, Bengtsson-Palme J, Berlin A, Branco S, Chomnunti P, Dissanayake A, Drenkhan R, Friberg H, Frøslev TG, Halwachs B, Hartmann M, Henricot B, Jayawardena R, Jumpponen A, Kauserud H, Koskela S, Kulik T, Liimatainen K, Lindahl B, Lindner D, Liu J-K, Maharachchikumbura S, Manamgoda D, Martinsson S, Neves MA, Niskanen T, Nylinder S, Pereira OL, Pinho DB, Porter TM, Queloz V, Riit T, Sanchez-García M, de Sousa F, Stefaczyk E, Tadych M, Takamatsu S, Tian Q, Udayanga D, Unterseher M, Wang Z, Wikee S, Yan J, Larsson E, Larsson K-H, Kõljalg U, Abarenkov K: Improving ITS sequence data for identification of plant pathogenic fungi. Fungal Diversity, 67, 1, 11–19 (2014). doi: 10.1007/s13225-014-0291-8
  4. Bengtsson-Palme J, Boulund F, Edström R, Feizi A, Johnning A, Jonsson VA, Karlsson FH, Pal C, Pereira MB, Rehammar A, Sánchez J, Sanli K, Thorell K: Strategies to improve usability and preserve accuracy in biological sequence databases. Proteomics, Early view (2016). doi: 10.1002/pmic.201600034

I have had the pleasure to be chosen as a speaker for next week’s (ten days from now) Swedish Bioinformatics Workshop. My talk is entitled “Turn up the signal – wipe out the noise: Gaining insights into bacterial community functions using metagenomic data“, and will largely deal with the same questions as my talk on EDAR3 in May this year. As then, the talk will highlight the some particular pitfalls related to interpretation of data, and exemplify how flawed analysis practices can result in misleading conclusions regarding community function, and use examples from our studies of environments subjected to pharmaceutical pollution in India, the effect of travel on the human resistome, and modern municipal wastewater treatment processes.

The talk will take place on Thursday, September 24, 2015 at 16:30. The full program for the conference can be found here. And also, if you want a sneak peak of the talk, you can drop by on Friday 13.00 at Chemistry and Molecular Biology, where I will give a seminar on the same topic in the Monthly Bioinformatic Practical Meetings series.

I would like to bring your attention to that the abstract deadline for the Swedish Bioinformatics Workshop held in Gothenburg in October has been extended to September 15. So hurry on and contribute with your latest research, we look forward to get to know what you’re doing!

I am part of the organizing committee for the Swedish Bioinformatics Workshop (#SBW2014) that will be held October 23-24 this year in Gothenburg. I would like to invite you all, especially master/PhD students and PostDocs in Sweden, to come and share the event with us!

SBW is an annual event that has been organized by the different universities in Sweden. This year it will take place at the Wallenberg Conference Centre in Gothenburg and is arranged by both University of Gothenburg and Chalmers University of Technology. SBW2014 will, as the tradition abides, be a meeting point for PhD students and postdocs working with any kind of bioinformatics within Sweden and is therefore free of charge for these groups. We are proud to announce a program including both invited speakers – such as Mick Watson from the Roslin institute, Dawn Field from University of Oxford, and Joakim Lundeberg from KTH – along with participant presentations and poster sessions. This year, the program will also contain a number of workshop sessions where hands-on problems will be used as starting points for discussions on new bioinformatics approaches to these problems. This will provide opportunities for attendees with different methodological backgrounds to interact and work together to find synergies between fields and come up with creative solutions.

More information about the event including registration and abstract submission can be found at www.sbw2014.se.

I, and the rest of the organizers, look forward to meeting you in Gothenburg in October!

Webpage: http://www.sbw2014.se

Facebook: https://www.facebook.com/events/1450513325188910/

Google+: https://plus.google.com/events/cuhlpovcc275stut854dk5ussnk

If you want, you can spread the word, for example using this flyer!

Science for Life Laboratories (SciLifeLab) in Stockholm will host a metagenome data analysis workshop on May 21-23, in which I will participate as a tutorial assistant. Additionally, our group leader Joakim Larsson will be giving a lecture about how we use metagenomics to assess the environmental reservoir of antibiotic resistance genes (much of my recent work will likely go into that). I hope to meet you there, so don’t forget to register!

Confirmed speakers:
Lex Nederbragt, Oslo University, Norway
Saskia Smits, Erasmus University Rotterdam, Netherlands
Joakim Larsson, Göteborg University, Sweden
Paul Wilmes, University of Luxembourg, Luxembourg
Anders Andersson, SciLifeLab, Sweden
Noan Le Bescot, UPMC (Tara expedition), France

The workshop is part of the AllBio Bioinformatics initiative.

Those attending the Metagenomics lab (part of the basic NGS course for PhD students given at GU this week), can find the material for the lab on this page:
http://microbiology.se/ngs-metagenomics-lab/
Of course, the page is open for anyone else as well, although you won’t get the support that the GU students are given.

The newly formed bioinformatics network for PhD students in Gothenburg (GoBiG), will have an introductory meeting next week, on thursday the 26th at Chalmers. See this page for more info.

The 11th annual meeting of PhD students and Postdoc researchers in Bioinformatics in Sweden will take place in Lund the 29-30 September. The workshop is an opportunity for young researchers to meet, exchange ideas, and keep up to date with the growing body of knowledge. I will go there, and you should be there too! Besides, it’s free for PhD students and Postdocs! All info can be found at the workshop website. The last time I was there (2010) really fueled some interesting discussions, and I am really looking forward to the event this year. Hope to meet you there, fellow Swedish bioinformaticians!