CLEVER
Classification of Latent and Established Variants of Extant antibiotic Resistance
CLEVER is a database resource for antibiotic resistance genes (ARGs). It contains information on verified ARGs gathered from ResFinder, CARD and ResFinderFG. It also contains predicted ARGs from the following collections:
- Inda-Díaz JS, Lund D, Parras-Moltó M, Johnning A, Bengtsson-Palme J, Kristiansson E. Latent antibiotic resistance genes are abundant, diverse, and mobile in human, animal, and environmental microbiomes. Microbiome. 2023;11(1):44. Published 2023 Mar 8. doi:10.1186/s40168-023-01479-0
The current CLEVER version is 1.0, released on March 20, 2026.
The database can be downloaded from here for offline usage, or browsed in the tables below. The code base is also hosted on GitHub.
This is a full list of CLEVER families (90% identity ARG clusters)
You can filter the list using the buttons below. You can also select to look at the complete list of variants or the CLEVER lineages (70% identity ARG clusters).
| Gene name | Class | Established | Mobile | Verified | Source |
|---|---|---|---|---|---|
| aac(6')-Ib | aac6p | E | M | V | ResFinder |
| aac(6')-30/aac(6')-Ib' | aac6p | E | M | V | ResFinder |
| aac(6')-Iaj | aac6p | E | C | V | ResFinder |
| aac(6')-Ian | aac6p | E | M | V | ResFinder |
| aac(6')-Iak | aac6p | E | C | V | ResFinder |
| aac(6') | aac6p | E | M | V | ResFinder |
| aac(6')-Iid | aac6p | E | C | V | ResFinder |
| aac(6')-Iih | aac6p | E | C | V | ResFinder |
| aac(6')-Iz | aac6p | E | C | V | ResFinder |
| aac(6')-29 | aac6p | E | M | V | ResFinder |
| aac(6')-I | aac6p | E | M | V | ResFinder |
| aac(6')-I | aac6p | E | M | V | ResFinder |
| aac(6')-I | aac6p | E | C | V | ResFinder |
| aac(6')-Il | aac6p | E | M | V | ResFinder |
| aac(6')-Ia | aac6p | E | M | V | ResFinder |
| aac(6')-Iag | aac6p | E | M | V | ResFinder |
| aac(2')-IIa | aac2p | E | M | V | ResFinder |
| kamB | unc | E | C | V | ResFinder |
| grmO | unc | E | C | V | ResFinder |
| fmrO | unc | E | C | V | ResFinder |
| grmB | unc | E | C | V | ResFinder |
| grmA | unc | E | C | V | ResFinder |
| kgmB | unc | E | C | V | ResFinder |
| sgm | unc | E | C | V | ResFinder |
| aph(3')-VI | aph3p | E | M | V | ResFinder |
| aph(3')-IX | aph3p | E | M | V | ResFinder |
| ant(6)-Ia/aad(6) | ant | E | M | V | ResFinder |
| aadA13 | aad | E | M | V | ResFinder |
| aadA11 | aad | E | M | V | ResFinder |
| aadA7 | aad | E | M | V | ResFinder |
| aadA | aad | E | M | V | ResFinder |
| aph(2'')-Ib | aph2b | E | M | V | ResFinder |
| aph(7'')-Ia | aph7b | E | M | V | ResFinder |
| aph(9)-Ia | aph9 | E | C | V | ResFinder |
| aph(6)-Ia | aph6 | E | C | V | ResFinder |
| aph(6)-Id | aph6 | E | M | V | ResFinder |
| aph(3'')-Ia | aph3b | E | C | V | ResFinder |
| aph(3'')-Ib | aph3b | E | M | V | ResFinder |
| aadE-Cc | aad | E | C | V | ResFinder |
| ant(2'')-Ia | ant | E | M | V | ResFinder |
| aph(3')-XV | aph3p | E | M | V | ResFinder |
| aph(3')-III | aph3p | E | M | V | ResFinder |
| aph(3')-Va | aph3p | E | C | V | ResFinder |
| aph(3')-Vb | aph3p | E | C | V | ResFinder |
| aph(3')-IIa | aph3p | E | M | V | ResFinder |
| aph(3')-IIb | aph3p | E | M | V | ResFinder |
| aph(3')-Ia | aph3p | E | M | V | ResFinder |
| aph(2'')-Ih | aph2b | E | M | V | ResFinder |
| aph(2'')-Ig | aph2b | E | M | V | ResFinder |
| aph(2'')-If | aph2b | E | M | V | ResFinder |