The fall semester has begun, and with that we have started a new round of recordings of the Microbiology Lab Pod. Our fourth episode was recorded on August 20, and the now-familiar crew (Johan Bengtsson-Palme, Emil Burman, Haveela Kunche and Anna Abramova) has been augmented with two new master students in the lab: Sebastian Wettersten and Mahbuba Lubna Akter. This time, we discuss microbial communities of dead and alive deep-sea hydrothermal vents, look at a model system for pathogenic biofilm formation in the lungs, and check in on why patients with covid-19 commonly lose their sense of smell.
The specific papers discussed in the pod (with approximate timings) are as follows:
- 11:30 – Hou, J., Sievert, S.M., Wang, Y. et al., 2020. Microbial succession during the transition from active to inactive stages of deep-sea hydrothermal vent sulfide chimneys. Microbiome 8, 102. https://doi.org/10.1186/s40168-020-00851-8
- 28:45 – Harrington, N.E., Sweeney, E., Harrison, F., 2020. Building a better biofilm – Formation of in vivo-like biofilm structures by Pseudomonas aeruginosa in a porcine model of cystic fibrosis lung infection. Biofilm 2, 100024. https://doi.org/10.1016/j.bioflm.2020.100024
- 52:30 – Brann, D.H., Tsukahara, T., Weinreb, C., et al., 2020. Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia. Science Advances 6, eabc5801. https://doi.org/10.1126/sciadv.abc5801
- 71:45 – Chen, M., Shen, W., Rowan, N.R., et al., 2020. Elevated ACE2 expression in the olfactory neuroepithelium: implications for anosmia and upper respiratory SARS-CoV-2 entry and replication. European Respiratory Journal 2001948. https://doi.org/10.1183/13993003.01948-2020
- 77:15 – Zhang, X., Wang, J., 2020. Deducing the Dose-response Relation for Coronaviruses from COVID-19, SARS and MERS Meta-analysis Results. medRxiv. https://doi.org/10.1101/2020.06.26.20140624
- 78:30 – Sekine, T., Perez-Potti, A., Rivera-Ballesteros, O., et al., 2020. Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19. Cell. https://doi.org/10.1016/j.cell.2020.08.017
- 79:45 – Mateus, J., Grifoni, A., Tarke, A., et al., 2020. Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans. Science eabd3871. https://doi.org/10.1126/science.abd3871
- 80:30 – Lv, H., Wu, N.C., Tsang, O.T.-Y., et al., 2020. Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections. Cell Reports 31, 107725. https://doi.org/10.1016/j.celrep.2020.107725
The podcast was recorded on August 20, 2020. If you want to reach out to us with comments, suggestions or other feedback, please send an e-mail to podcast at microbiology dot se or contact @bengtssonpalme via Twitter. The music that can be heard on the pod is composed by Johan Bengtsson-Palme and is taken from the album Cafe Phonocratique.